28 Mar, 2012
Accessing Hiv Hiv
Background
HIV spread continues at high rates from infected persons to their sexual partners. In 2009, an estimated 2.6 million new infections occurred globally. People living with HIV (PLHIV) receiving treatment are in contact with health workers and therefore exposed to prevention messages. By contrast, PLHIV not receiving ART often fall outside the ambit of prevention programs. There is little information on their sexual risk behaviors. This study in Mombasa Kenya therefore explored sexual behaviors of PLHIV not receiving any HIV treatment.
Results
Using modified targeted snowball sampling, 698 PLHIV were recruited through community health workers and HIV-positive peer counsellors.
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17 Mar, 2012
Meals Meals Trigger
High-fat meals might boost inflammation in people with type 2 diabetes, a new study says.
Inflammation is associated with many diabetes-related complications, such as heart disease.
who ate a high-fat meal after an overnight fast.
The researchers compared levels of endotoxins in the participants blood before and after they ate the meal.
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9 Mar, 2012
Carts Study Rectal Cancer Rectum
Published: 15 December 2011
Background The CARTS study is a multicenter feasibility study, investigating the role of rectum saving surgery for distal rectal cancer. Methods/Design Patients with a clinical T1-3 N0 M0 rectal adenocarcinoma below 10 cm from the anal verge will receive neoadjuvant chemoradiation therapy (25 fractions of 2 Gy with concurrent capecitabine). Transanal Endoscopic Microsurgery (TEM) will be performed 8 – 10 weeks after the end of the preoperative treatment depending on the clinical response. Primary objective is to determine the number of patients with a (near) complete pathological response after chemoradiation therapy and TEM.
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4 Mar, 2012
Hiv Military Prospective
Background
Although highly active antiretroviral therapy (HAART) has improved HIV survival, some patients receiving therapy are still dying. This analysis was conducted to identify factors associated with increased risk of post-HAART mortality.
Methods
We evaluated baseline (prior to HAART initiation) clinical, demographic and laboratory factors (including CD4+ count and HIV RNA level) for associations with subsequent mortality in 1,600 patients who began HAART in a prospective observational cohort of HIV-infected U.S. military personnel.
Results
Cumulative mortality was 5%, 10% and 18% at 4, 8 and 12 years post-HAART.
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26 Feb, 2012
Nerve Damage Study
A new study finds that people with prediabetes are no more likely to have a type of nerve damage called small fiber polyneuropathy than healthy people, a finding that contradicts two decades of medical reports.
The Mayo Clinic researchers said the results from their five-year study of 550 people suggest that doctors should look for causes other than prediabetes in patients with painful small fiber polyneuropathy.
Prediabetes, also called borderline diabetes, is higher than normal blood sugar levels, but not high enough to be considered diabetes.
It is highly unlikely that impaired glucose or associated metabolic derangements cause polyneuropathy, at least not to the high frequency previously reported, lead author and neurologist Dr.
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